Colorado Attorney General Cynthia Coffman has joined a broad coalition of attorneys general demanding information from opioid manufacturers and distributors as part of a multi-state investigation into the causes of the painkiller epidemic, her office said Tuesday.

A bipartisan group of 41 attorneys general served subpoenas Monday on Endo Pharmaceuticals, Janssen Pharmaceuticals, Teva Pharmaceuticals/Cephalon, Inc. and Allergan plc, and served a supplemental subpoena on Purdue Pharma, Coffman, a Republican, announced. They also sent letters asking for information from distributors AmerisourceBergen, Cardinal Health and McKesson.

The states are investigating whether the industry has engaged in illegal marketing and sales activities that contributed to a surge in opioid prescriptions and drug overdose deaths in recent decades.

“There is no magic bullet to solve this crisis, but I am committed to working with partners throughout Colorado and the country to find a solution,” Coffman said in a written statement. “This investigation is another step in a continuing effort by my office to help those impacted by opioid addiction and to hold accountable those who contributed to this epidemic in violation of Colorado law.”

The investigation could lead to a national settlement with the states if the industry cooperates, and there’s some indication drugmakers and distributors will engage in a discussion about the matter, the Associated Press reported.

Prescription opioids were involved in more than 33,000 deaths nationwide last year – including 300 in Colorado – according to the Centers for Disease Control and Prevention. U.S. patients receive as many as 200 million opioid prescriptions annually, and sales of the powerful painkillers nearly quadruped between 1999 and 2014, Coffman noted.

“The scourge of opioid addiction has impacted every corner of our state,” she said. “Our doctors, nurses, and first responders have been working tirelessly, oftentimes in dangerous circumstances, to save those battling addiction. Our nonprofits and government agencies have been fighting an uphill battle to help those trapped in the cycle of addiction. And our churches and schools have been shouldering a heavy burden helping to console, counsel, and educate those who’ve lost loved ones, including the children who have been orphaned or abandoned due to this to this deadly epidemic.”

The Healthcare Distribution Alliance said in a statement that it isn’t responsible for the volume of opioid prescriptions but wants to work on solving the public health crisis. In addition, drug industry representative PhRMA declined to comment on the investigation but said it’s s trying to deter and prevent drug abuse, the AP reported.

The Associated Press contributed to this report.